Rejuvenation
Mesotherapy/Lipodissolve,...not in Loudoun, ..not liposuction
Liposuction Cosmetic Plastic Surgery for Northern Virginia, West Virginia, Maryland, & Washington DC
Mesotherapy was developed in France in 1952. It was believed that injecting various highly concentrated compounds into the dermis could produce a positive physiological effect on vascular and lymphatic systems near the skin. Traditionally, the ingredients are injected into the deep dermis or mesoderm. Mesotherapy injection solutions can contain various combinations of substances that may include vitamins, minerals, stimulants, plant extracts, vasodilators, hormones, enzymes, and drugs such as NSAIDs, theophylline and isoproterenol. Web site descriptions of Mesotherapy treatments offer only vague details of the ingredients. Many practitioners have their own formulas, which are often kept secret or revealed only through fee-for-service physician courses.
Injections are recommended for a wide range of conditions including pain management, sports injuries, cellulite, wrinkles, alopecia, psoriasis, weight loss and body contouring. For decades, Mesotherapy was mostly used in Europe. It did not appear in the U.S. until the late 1990s. Mesotherapy is not a type of liposuction.
Lipodissolve
Not to be confused with Mesotherapy, lipolysis treatments also claim to reduce or eliminate unwanted local accumulations of fat. The difference between Mesotherapy and lipolysis is the ingredients and injection locations. Lipolysis is injected into the subcutaneous fat and Mesotherapy injects into the mesoderm. Lipolysis is typically done with trade-named products such as Lipodissolve and Lipostabil or with private formulations provided by compounding pharmacies. The one common ingredient in all injection Lipolysis formulations is phosphatidylcholine (PPC). PPC seems to be the primary component of injection Lipolysis formulas used in Europe and South America, although vitamins and other ingredients may be added.
In the U.S., sodium deoxycholate (DC), a component of bile, is a second major ingredient used to keep the PPC soluble and in an injectable form without precipitating out of solution.
PPC and DC are both approved by the FDA for use as surfactants and drug carriers. There is no FDA approval of either drug for subcutaneous injection for any purpose.
Contrary to advertising claims, injection Lipolysis does not actually ?melt? or ?dissolve? fat. Instead, PPC and/or DC appear to kill (lyse) adipocytes. It has been thought that treatment with PPC and DC reduces subcutaneous fat either by killing off the fat cell or due to direct toxic or surfactant effects. Studies have found that subcutaneous adipose tissue following PPC/DC treatments shows evidence of nodules of fat necrosis, threadlike strands of scar tissue, cell wall disruption, focal inflammation and collagen deposition. Lipodissolve is not a type of liposuction. Liposuction as the name implies, acutally removes the fat immediately using the liposuction instruments. Liposuction allows for the best controlled and precise removal of fat possible.
American Society for Aesthetic Plastic Surgery
The ASAPS does NOT endorse Lipodissolve and Mesotherapy treatments. These cosmetic treatments currently lack objective proof of safety and efficacy, as well as FDA approval. They are not the best method for fat removal. Cosmetic patients should be cautious about seeking treatment from people who may not be qualified to administer hundreds of injections that require very precise placement. It is best to avoid these cosmetic treatments to begin with.
Strong marketing has led to the surfacing of injection Lipolysis centers, franchises and spas all over the country. None of these centers are regulated.
Complications
In 2005, the Centers for Disease Control and Prevention reported ?mesotherapy? treatments for cosmetic fat reduction leading to an outbreak of skin infections, drainage or ulceration at the injection sites following at-home injections by a physician in Colombia. This case is the reason safety should be a patient?s first priority. Most common complication reported from injection Lipolysis are pain, tenderness to touch, redness, stinging/burning sensation, itching, edema and bruising. These occur soon after treatment and usually last for several days.
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